The anti-nausea drug Zofran may cause abnormal and potentially deadly heart rhythms , the U.S. Food and Drug Administration has warned.
The agency said Zofran, used to prevent nausea and vomiting caused by surgery, chemotherapy and radiation therapy, will be the subject of a further safety review. Zofran is made by GlaxoSmithKline PLC and also sold under the generic name ondansetron.
If you or a loved one suffered serious injury or death possibly as a result of taking Zofran, you should contact a Zofran attorney for a free evaluation of your case. Kline & Specter, PC, with more than 40 attorneys, several of whom are also highly experienced doctors, has the expertise to litigate Zofran cases and handles medical and product liability cases nationwide.
The FDA cautioned in September 2011 that Zofran can produce changes in the electrical activity of the heart (known as prolongation of the QT interval of the electrocardiogram) that can lead to an abnormal and potentially fatal heart rhythm, including Torsade de Pointes.
It noted that patients at particular risk for developing Torsade include those with underlying heart conditions, people predisposed to low levels of potassium and magnesium in the blood, and those taking other medications that lead to QT prolongation. Zofran is often used by cancer patients.
The FDA ordered GlaxoSmithKline to conduct a study to determine the degree to which Zofran may cause QT interval prolongation, with study results expected by Summer 2012. In the meantime, the government has ordered that the drug's label be changed to include "a warning to avoid use” in patients with congenital long QT syndrome.
Contact a Zofran lawyer today.